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Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs

Intrigued by the dynamics of the seemingly contradictory yet integrated cellular responses to the requisites of preserving telomere integrity while also efficiently repairing damaged DNA, we investigated roles of the telomere associated poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) tank...

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Detalles Bibliográficos
Autores principales: Dregalla, Ryan C., Zhou, Junqing, Idate, Rupa R., Battaglia, Christine L.R., Liber, Howard L., Bailey, Susan M.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993799/
https://www.ncbi.nlm.nih.gov/pubmed/21037379