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Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence

Inhibition of growth signaling pathways protects against aging and age-related diseases in parallel with reduced oxidative stress. The relationships between growth signaling, oxidative stress and aging remain unclear. Here we report that in Saccharomyces cerevisiae, alterations in growth signaling p...

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Detalles Bibliográficos
Autores principales: Weinberger, Martin, Mesquita, Ana, Carroll, Timothy, Marks, Laura, Yang, Hui, Zhang, Zhaojie, Ludovico, Paula, Burhans, William C.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993800/
https://www.ncbi.nlm.nih.gov/pubmed/21076178