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Estrogen Receptor β Exerts Tumor Repressive Functions in Human Malignant Pleural Mesothelioma via EGFR Inactivation and Affects Response to Gefitinib

BACKGROUND: The role of estrogen and estrogen receptors in oncogenesis has been investigated in various malignancies. Recently our group identified estrogen receptor beta (ERβ) expression as an independent prognostic factor in the progression of human Malignant Pleural Mesothelioma (MMe), but the un...

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Detalles Bibliográficos
Autores principales: Pinton, Giulia, Thomas, Warren, Bellini, Paolo, Manente, Arcangela Gabriella, Favoni, Roberto E., Harvey, Brian J., Mutti, Luciano, Moro, Laura
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993924/
https://www.ncbi.nlm.nih.gov/pubmed/21124760
http://dx.doi.org/10.1371/journal.pone.0014110