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Transgenic miR132 Alters Neuronal Spine Density and Impairs Novel Object Recognition Memory

Inducible gene expression plays a central role in neuronal plasticity, learning, and memory, and dysfunction of the underlying molecular events can lead to severe neuronal disorders. In addition to coding transcripts (mRNAs), non-coding microRNAs (miRNAs) appear to play a role in these processes. Fo...

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Detalles Bibliográficos
Autores principales: Hansen, Katelin F., Sakamoto, Kensuke, Wayman, Gary A., Impey, Soren, Obrietan, Karl
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993964/
https://www.ncbi.nlm.nih.gov/pubmed/21124738
http://dx.doi.org/10.1371/journal.pone.0015497