Cargando…
Transgenic miR132 Alters Neuronal Spine Density and Impairs Novel Object Recognition Memory
Inducible gene expression plays a central role in neuronal plasticity, learning, and memory, and dysfunction of the underlying molecular events can lead to severe neuronal disorders. In addition to coding transcripts (mRNAs), non-coding microRNAs (miRNAs) appear to play a role in these processes. Fo...
Autores principales: | Hansen, Katelin F., Sakamoto, Kensuke, Wayman, Gary A., Impey, Soren, Obrietan, Karl |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993964/ https://www.ncbi.nlm.nih.gov/pubmed/21124738 http://dx.doi.org/10.1371/journal.pone.0015497 |
Ejemplares similares
-
Targeted deletion of miR-132/-212 impairs memory and alters the hippocampal transcriptome
por: Hansen, Katelin F., et al.
Publicado: (2016) -
Profiling status epilepticus-induced changes in hippocampal RNA expression using high-throughput RNA sequencing
por: Hansen, Katelin F., et al.
Publicado: (2014) -
The miR-132/212 locus: a complex regulator of neuronal plasticity, gene expression and cognition
por: Aten, Sydney, et al.
Publicado: (2016) -
MicroRNAs: a potential interface between the circadian clock and human health
por: Hansen, Katelin F, et al.
Publicado: (2011) -
A Genome-Wide Screen of CREB Occupancy Identifies the RhoA Inhibitors Par6C and Rnd3 as Regulators of BDNF-Induced Synaptogenesis
por: Lesiak, Adam, et al.
Publicado: (2013)