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Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole

N-(2-methoxyphenyl)hydroxylamine is a human metabolite of the industrial and environmental pollutants and bladder carcinogens 2-methoxyaniline (o-anisidine) and 2-methoxynitrobenzene (o-nitroanisole). Here, we investigated the ability of hepatic microsomes from rat and rabbit to metabolize this reac...

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Detalles Bibliográficos
Autores principales: Naiman, Karel, Dračínská, Helena, Dračínský, Martin, Martínková, Markéta, Martínek, Václav, Hodek, Petr, Štícha, Martin, Frei, Eva, Stiborová, Marie
Formato: Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994023/
https://www.ncbi.nlm.nih.gov/pubmed/21218119
http://dx.doi.org/10.2478/v10102-010-0045-8