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Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole
N-(2-methoxyphenyl)hydroxylamine is a human metabolite of the industrial and environmental pollutants and bladder carcinogens 2-methoxyaniline (o-anisidine) and 2-methoxynitrobenzene (o-nitroanisole). Here, we investigated the ability of hepatic microsomes from rat and rabbit to metabolize this reac...
Autores principales: | Naiman, Karel, Dračínská, Helena, Dračínský, Martin, Martínková, Markéta, Martínek, Václav, Hodek, Petr, Štícha, Martin, Frei, Eva, Stiborová, Marie |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Slovak Toxicology Society SETOX
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994023/ https://www.ncbi.nlm.nih.gov/pubmed/21218119 http://dx.doi.org/10.2478/v10102-010-0045-8 |
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