Pharmacological targeting of β-adrenergic receptor functions abrogates NF-κB signaling and MMP-9 secretion in medulloblastoma cells

Targeting of the vascular endothelium compartment explains, in part, the therapeutic efficacy of the nonselective β-adrenergic antagonist propranolol against common endothelial tumors such as hemangiomas. In vitro, the antiangiogenic biological activity of propranolol was shown to inhibit human brai...

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Detalles Bibliográficos
Autores principales: Annabi, Borhane, Vaillancourt-Jean, Eric, Weil, Alexander G, Béliveau, Richard
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994204/
https://www.ncbi.nlm.nih.gov/pubmed/21124749
http://dx.doi.org/10.2147/OTT.S14503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994204/
https://www.ncbi.nlm.nih.gov/pubmed/21124749
http://dx.doi.org/10.2147/OTT.S14503

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