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The Contributions of Interlocking Loops and Extensive Nonlinearity to the Properties of Circadian Clock Models

BACKGROUND: Sensitivity and robustness are essential properties of circadian clock systems, enabling them to respond to the environment but resist noisy variations. These properties should be recapitulated in computational models of the circadian clock. Highly nonlinear kinetics and multiple loops a...

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Detalles Bibliográficos
Autores principales: Saithong, Treenut, Painter, Kevin J., Millar, Andrew J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994703/
https://www.ncbi.nlm.nih.gov/pubmed/21152419
http://dx.doi.org/10.1371/journal.pone.0013867