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Predicting DNA-Binding Specificities of Eukaryotic Transcription Factors
Today, annotated amino acid sequences of more and more transcription factors (TFs) are readily available. Quantitative information about their DNA-binding specificities, however, are hard to obtain. Position frequency matrices (PFMs), the most widely used models to represent binding specificities, a...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994704/ https://www.ncbi.nlm.nih.gov/pubmed/21152420 http://dx.doi.org/10.1371/journal.pone.0013876 |