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Predicting DNA-Binding Specificities of Eukaryotic Transcription Factors

Today, annotated amino acid sequences of more and more transcription factors (TFs) are readily available. Quantitative information about their DNA-binding specificities, however, are hard to obtain. Position frequency matrices (PFMs), the most widely used models to represent binding specificities, a...

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Detalles Bibliográficos
Autores principales: Schröder, Adrian, Eichner, Johannes, Supper, Jochen, Eichner, Jonas, Wanke, Dierk, Henneges, Carsten, Zell, Andreas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994704/
https://www.ncbi.nlm.nih.gov/pubmed/21152420
http://dx.doi.org/10.1371/journal.pone.0013876