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Independent Interactions of Phosphorylated β-Catenin with E-Cadherin at Cell-Cell Contacts and APC at Cell Protrusions

BACKGROUND: The APC tumour suppressor functions in several cellular processes including the regulation of β-catenin in Wnt signalling and in cell adhesion and migration. FINDINGS: In this study, we establish that in epithelial cells N-terminally phosphorylated β-catenin specifically localises to sev...

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Detalles Bibliográficos
Autores principales: Faux, Maree C., Coates, Janine L., Kershaw, Nadia J., Layton, Meredith J., Burgess, Antony W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994709/
https://www.ncbi.nlm.nih.gov/pubmed/21152425
http://dx.doi.org/10.1371/journal.pone.0014127