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Mesenchymal/Stromal Gene Expression Signature Relates to Basal-Like Breast Cancers, Identifies Bone Metastasis and Predicts Resistance to Therapies

BACKGROUND: Mounting clinical and experimental evidence suggests that the shift of carcinomas towards a mesenchymal phenotype is a common paradigm for both resistance to therapy and tumor recurrence. However, the mesenchymalization of carcinomas has not yet entered clinical practice as a crucial dia...

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Detalles Bibliográficos
Autores principales: Marchini, Cristina, Montani, Maura, Konstantinidou, Georgia, Orrù, Rita, Mannucci, Silvia, Ramadori, Giorgio, Gabrielli, Federico, Baruzzi, Anna, Berton, Giorgio, Merigo, Flavia, Fin, Stefania, Iezzi, Manuela, Bisaro, Brigitte, Sbarbati, Andrea, Zerani, Massimo, Galiè, Mirco, Amici, Augusto
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994727/
https://www.ncbi.nlm.nih.gov/pubmed/21152434
http://dx.doi.org/10.1371/journal.pone.0014131