Statins Inhibit Angiotensin II/Smad Pathway and Related Vascular Fibrosis, by a TGF-β-Independent Process

We have recently described that in an experimental model of atherosclerosis and in vascular smooth muscle cells (VSMCs) statins increased the activation of the Smad pathway by transforming growth factor-β (TGF-β), leading to an increase in TGF-β-dependent matrix accumulation and plaque stabilization...

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Detalles Bibliográficos
Autores principales: Rodrigues Díez, Raúl, Rodrigues-Díez, Raquel, Lavoz, Carolina, Rayego-Mateos, Sandra, Civantos, Esther, Rodríguez-Vita, Juan, Mezzano, Sergio, Ortiz, Alberto, Egido, Jesús, Ruiz-Ortega, Marta
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994748/
https://www.ncbi.nlm.nih.gov/pubmed/21152444
http://dx.doi.org/10.1371/journal.pone.0014145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994748/
https://www.ncbi.nlm.nih.gov/pubmed/21152444
http://dx.doi.org/10.1371/journal.pone.0014145

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