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Selective Ablation of the Androgen Receptor in Mouse Sertoli Cells Affects Sertoli Cell Maturation, Barrier Formation and Cytoskeletal Development

The observation that mice with a selective ablation of the androgen receptor (AR) in Sertoli cells (SC) (SCARKO mice) display a complete block in meiosis supports the contention that SC play a pivotal role in the control of germ cell development by androgens. To delineate the physiological and molec...

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Detalles Bibliográficos
Autores principales: Willems, Ariane, Batlouni, Sergio R., Esnal, Arantza, Swinnen, Johannes V., Saunders, Philippa T. K., Sharpe, Richard M., França, Luiz R., De Gendt, Karel, Verhoeven, Guido
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994754/
https://www.ncbi.nlm.nih.gov/pubmed/21152390
http://dx.doi.org/10.1371/journal.pone.0014168