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The membrane-spanning domain of gp41 plays a critical role in intracellular trafficking of the HIV envelope protein
BACKGROUND: The sequences of membrane-spanning domains (MSDs) on the gp41 subunit are highly conserved among many isolates of HIV-1. The GXXXG motif, a potential helix-helix interaction motif, and an arginine residue (rare in hydrophobic MSDs) are especially well conserved. These two conserved eleme...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994783/ https://www.ncbi.nlm.nih.gov/pubmed/21073746 http://dx.doi.org/10.1186/1742-4690-7-95 |