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The membrane-spanning domain of gp41 plays a critical role in intracellular trafficking of the HIV envelope protein

BACKGROUND: The sequences of membrane-spanning domains (MSDs) on the gp41 subunit are highly conserved among many isolates of HIV-1. The GXXXG motif, a potential helix-helix interaction motif, and an arginine residue (rare in hydrophobic MSDs) are especially well conserved. These two conserved eleme...

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Detalles Bibliográficos
Autores principales:	Miyauchi, Kosuke, Curran, A Rachael, Long, Yufei, Kondo, Naoyuki, Iwamoto, Aikichi, Engelman, Donald M, Matsuda, Zene
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994783/ https://www.ncbi.nlm.nih.gov/pubmed/21073746 http://dx.doi.org/10.1186/1742-4690-7-95

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