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The gene-reduction effect of chromosomal losses detected in gastric cancers

BACKGROUND: The level of loss of heterozygosity (LOH) that reduces a gene dose and exerts a cell-adverse effect is known to be a parameter for the genetic staging of gastric cancers. This study investigated if the cell-adverse effect induced with the gene reduction was a rate-limiting factor for the...

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Detalles Bibliográficos
Autores principales: Hong, Seung-Jin, Jeon, Eun-Jung, Oh, Jung-Hwan, Seo, Eun-Joo, Choi, Sang-Wook, Rhyu, Mun-Gan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994793/
https://www.ncbi.nlm.nih.gov/pubmed/21092121
http://dx.doi.org/10.1186/1471-230X-10-138