IL-2 as a therapeutic target for the restoration of Foxp3(+ )regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease

Peripheral immune tolerance requires a finely controlled balance between tolerance to self-antigens and protective immunity against enteric and invading pathogens. Self-reactive T cells sometimes escape thymic clonal deletion, and can subsequently provoke autoimmune diseases such as type 1 diabetes...

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Detalles Bibliográficos
Autores principales: d'Hennezel, Eva, Kornete, Mara, Piccirillo, Ciriaco A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994816/
https://www.ncbi.nlm.nih.gov/pubmed/21059266
http://dx.doi.org/10.1186/1479-5876-8-113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994816/
https://www.ncbi.nlm.nih.gov/pubmed/21059266
http://dx.doi.org/10.1186/1479-5876-8-113

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