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MATH5 controls the acquisition of multiple retinal cell fates

Math5-null mutation results in the loss of retinal ganglion cells (RGCs) and in a concurrent increase of amacrine and cone cells. However, it remains unclear whether there is a cell fate switch of Math5-lineage cells in the absence of Math5 and whether MATH5 cell-autonomously regulates the different...

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Detalles Bibliográficos
Autores principales: Feng, Liang, Xie, Zheng-hua, Ding, Qian, Xie, Xiaoling, Libby, Richard T, Gan, Lin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994854/
https://www.ncbi.nlm.nih.gov/pubmed/21087508
http://dx.doi.org/10.1186/1756-6606-3-36