Cargando…

Estimating the evidence of selection and the reliability of inference in unigenic evolution

BACKGROUND: Unigenic evolution is a large-scale mutagenesis experiment used to identify residues that are potentially important for protein function. Both currently-used methods for the analysis of unigenic evolution data analyze 'windows' of contiguous sites, a strategy that increases sta...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernandes, Andrew D, Kleinstiver, Benjamin P, Edgell, David R, Wahl, Lindi M, Gloor, Gregory B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994857/
https://www.ncbi.nlm.nih.gov/pubmed/21059250
http://dx.doi.org/10.1186/1748-7188-5-35