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Estimating the evidence of selection and the reliability of inference in unigenic evolution

BACKGROUND: Unigenic evolution is a large-scale mutagenesis experiment used to identify residues that are potentially important for protein function. Both currently-used methods for the analysis of unigenic evolution data analyze 'windows' of contiguous sites, a strategy that increases sta...

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Detalles Bibliográficos
Autores principales:	Fernandes, Andrew D, Kleinstiver, Benjamin P, Edgell, David R, Wahl, Lindi M, Gloor, Gregory B
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994857/ https://www.ncbi.nlm.nih.gov/pubmed/21059250 http://dx.doi.org/10.1186/1748-7188-5-35

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