T Cell Receptor Signal Initiation Induced by Low-Grade Stimulation Requires the Cooperation of LAT in Human T Cells

BACKGROUND: One of the earliest activation events following stimulation of the T cell receptor (TCR) is the phosphorylation of the immunoreceptor tyrosine-based activation motifs (ITAMs) within the CD3-associated complex by the Src family kinase Lck. There is accumulating evidence that a large pool...

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Detalles Bibliográficos
Autores principales: Dong, Shen, Corre, Béatrice, Nika, Konstantina, Pellegrini, Sandra, Michel, Frédérique
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994893/
https://www.ncbi.nlm.nih.gov/pubmed/21152094
http://dx.doi.org/10.1371/journal.pone.0015114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994893/
https://www.ncbi.nlm.nih.gov/pubmed/21152094
http://dx.doi.org/10.1371/journal.pone.0015114

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