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Association between Acquired Uniparental Disomy and Homozygous Mutations and HER2/ER/PR Status in Breast Cancer

BACKGROUND: Genetic alterations in cellular signaling networks are a hallmark of cancer, however, effective methods to discover them are lacking. A novel form of abnormality called acquired uniparental disomy (aUPD) was recently found to pinpoint the region of mutated genes in various cancers, there...

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Detalles Bibliográficos
Autores principales: Tuna, Musaffe, Smid, Marcel, Zhu, Dakai, Martens, John W. M., Amos, Christopher I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994899/
https://www.ncbi.nlm.nih.gov/pubmed/21152100
http://dx.doi.org/10.1371/journal.pone.0015094