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Vaccination-Induced Noncytolytic Effects in the Acute Phase of SHIV Infection

Many studies have shown that vaccines inducing CD8+ T cell responses can reduce viral loads and preserve CD4+ T cell numbers in monkey models of HIV infection. The mechanism of viral control by the vaccine-induced CD8+ T cells is usually assumed to be cytolysis of infected cells. However, in additio...

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Detalles Bibliográficos
Autores principales: Petravic, Janka, Davenport, Miles P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994900/
https://www.ncbi.nlm.nih.gov/pubmed/21152101
http://dx.doi.org/10.1371/journal.pone.0015083