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Decreased caveolin-1 levels contribute to fibrosis and deposition of extracellular IGFBP-5

Our previous studies have demonstrated increased expression of insulin-like growth factor binding protein-5 (IGFBP-5) in fibrotic tissues and IGFBP-5 induction of extracellular matrix (ECM) components. The mechanism resulting in increased IGFBP-5 in the extracellular milieu of fibrotic fibroblasts i...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Yukie, Yasuoka, Hidekata, Stolz, Donna B, Feghali-Bostwick, Carol A
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995014/
https://www.ncbi.nlm.nih.gov/pubmed/20345844
http://dx.doi.org/10.1111/j.1582-4934.2010.01063.x