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Structure and function of the regulatory HRDC domain from human Bloom syndrome protein

The helicase and RNaseD C-terminal (HRDC) domain, conserved among members of the RecQ helicase family, regulates helicase activity by virtue of variations in its surface residues. The HRDC domain of Bloom syndrome protein (BLM) is known as a critical determinant of the dissolution function of double...

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Detalles Bibliográficos
Autores principales: Kim, Young Mee, Choi, Byong-Seok
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995041/
https://www.ncbi.nlm.nih.gov/pubmed/20639533
http://dx.doi.org/10.1093/nar/gkq586