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Insights into the molecular determinants involved in cap recognition by the vaccinia virus D10 decapping enzyme

Decapping enzymes are required for the removal of the 5′-end (m7)GpppN cap of mRNAs to allow their decay in cells. While many cap-binding proteins recognize the cap structure via the stacking of the methylated guanosine ring between two aromatic residues, the precise mechanism of cap recognition by...

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Detalles Bibliográficos
Autores principales: Soulière, Marie F., Perreault, Jean-Pierre, Bisaillon, Martin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995054/
https://www.ncbi.nlm.nih.gov/pubmed/20639534
http://dx.doi.org/10.1093/nar/gkq628