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Insights into the molecular determinants involved in cap recognition by the vaccinia virus D10 decapping enzyme
Decapping enzymes are required for the removal of the 5′-end (m7)GpppN cap of mRNAs to allow their decay in cells. While many cap-binding proteins recognize the cap structure via the stacking of the methylated guanosine ring between two aromatic residues, the precise mechanism of cap recognition by...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995054/ https://www.ncbi.nlm.nih.gov/pubmed/20639534 http://dx.doi.org/10.1093/nar/gkq628 |