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A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons

CPEB3 is a sequence-specific RNA-binding protein and represses translation of its target mRNAs in neurons. Here, we have identified a novel function of CPEB3 as to interact with Stat5b and inhibit its transcription activity in the nucleus without disrupting dimerization, DNA binding and nuclear loca...

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Detalles Bibliográficos
Autores principales: Peng, Shu-Chun, Lai, Yen-Ting, Huang, Hsi-Yuan, Huang, Hsien-Da, Huang, Yi-Shuian
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995057/
https://www.ncbi.nlm.nih.gov/pubmed/20639532
http://dx.doi.org/10.1093/nar/gkq634