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A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons
CPEB3 is a sequence-specific RNA-binding protein and represses translation of its target mRNAs in neurons. Here, we have identified a novel function of CPEB3 as to interact with Stat5b and inhibit its transcription activity in the nucleus without disrupting dimerization, DNA binding and nuclear loca...
Autores principales: | Peng, Shu-Chun, Lai, Yen-Ting, Huang, Hsi-Yuan, Huang, Hsien-Da, Huang, Yi-Shuian |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995057/ https://www.ncbi.nlm.nih.gov/pubmed/20639532 http://dx.doi.org/10.1093/nar/gkq634 |
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