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A molecular clamp ensures allosteric coordination of peptidyltransfer and ligand binding to the ribosomal A-site
Although the ribosome is mainly comprised of rRNA and many of its critical functions occur through RNA–RNA interactions, distinct domains of ribosomal proteins also participate in switching the ribosome between different conformational/functional states. Prior studies demonstrated that two extended...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995063/ https://www.ncbi.nlm.nih.gov/pubmed/20660012 http://dx.doi.org/10.1093/nar/gkq641 |