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Dynamics of a novel centromeric histone variant CenH3 reveals the evolutionary ancestral timing of centromere biogenesis

The centromeric histone H3 variant (CenH3) serves to target the kinetochore to the centromeres and thus ensures correct chromosome segregation during mitosis and meiosis. The Dictyostelium H3-like variant H3v1 was identified as the CenH3 ortholog. Dictyostelium CenH3 has an extended N-terminal domai...

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Detalles Bibliográficos
Autores principales: Dubin, Manu, Fuchs, Jörg, Gräf, Ralph, Schubert, Ingo, Nellen, Wolfgang
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995078/
https://www.ncbi.nlm.nih.gov/pubmed/20675719
http://dx.doi.org/10.1093/nar/gkq664