A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function

DNA topoisomerases manage chromosome supercoiling and organization in all forms of life. Gyrase, a prokaryotic heterotetrameric type IIA topo, introduces negative supercoils into DNA by an ATP-dependent strand passage mechanism. All gyrase orthologs rely on a homologous set of catalytic domains for...

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Detalles Bibliográficos
Autores principales: Schoeffler, Allyn J., May, Andrew P., Berger, James M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995079/
https://www.ncbi.nlm.nih.gov/pubmed/20675723
http://dx.doi.org/10.1093/nar/gkq665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995079/
https://www.ncbi.nlm.nih.gov/pubmed/20675723
http://dx.doi.org/10.1093/nar/gkq665

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