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The role of transcription factories-mediated interchromosomal contacts in the organization of nuclear architecture

Using numerical simulations, we investigate the underlying physical effects responsible for the overall organization of chromosomal territories in interphase nuclei. In particular, we address the following three questions: (i) why are chromosomal territories with relatively high transcriptional acti...

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Detalles Bibliográficos
Autores principales: Dorier, Julien, Stasiak, Andrzej
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995080/
https://www.ncbi.nlm.nih.gov/pubmed/20675721
http://dx.doi.org/10.1093/nar/gkq666