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The role of transcription factories-mediated interchromosomal contacts in the organization of nuclear architecture
Using numerical simulations, we investigate the underlying physical effects responsible for the overall organization of chromosomal territories in interphase nuclei. In particular, we address the following three questions: (i) why are chromosomal territories with relatively high transcriptional acti...
Autores principales: | Dorier, Julien, Stasiak, Andrzej |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995080/ https://www.ncbi.nlm.nih.gov/pubmed/20675721 http://dx.doi.org/10.1093/nar/gkq666 |
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