Cargando…
Position and motions of the S4 helix during opening of the Shaker potassium channel
The four voltage sensors in voltage-gated potassium (Kv) channels activate upon membrane depolarization and open the pore. The location and motion of the voltage-sensing S4 helix during the early activation steps and the final opening transition are unresolved. We studied Zn(2+) bridges between two...
Autores principales: | , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995149/ https://www.ncbi.nlm.nih.gov/pubmed/21115696 http://dx.doi.org/10.1085/jgp.201010517 |