A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating

Store-operated Ca(2+) entry is controlled by the interaction of stromal interaction molecules (STIMs) acting as endoplasmic reticulum ER Ca(2+) sensors with calcium release–activated calcium (CRAC) channels (CRACM1/2/3 or Orai1/2/3) in the plasma membrane. Here, we report structural requirements of...

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Detalles Bibliográficos
Autores principales: Lis, Annette, Zierler, Susanna, Peinelt, Christine, Fleig, Andrea, Penner, Reinhold
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995155/
https://www.ncbi.nlm.nih.gov/pubmed/21115697
http://dx.doi.org/10.1085/jgp.201010484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995155/
https://www.ncbi.nlm.nih.gov/pubmed/21115697
http://dx.doi.org/10.1085/jgp.201010484

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