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On the mechanism of CFTR inhibition by a thiazolidinone derivative

The effects of a thiazolidinone derivative, 3-[(3-trifluoromethyl)phenyl]-5-[(4-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone (or CFTRinh-172), on cystic fibrosis transmembrane conductance regulator (CFTR) gating were studied in excised inside-out membrane patches from Chinese hamster ovary cel...

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Detalles Bibliográficos
Autores principales: Kopeikin, Zoia, Sohma, Yoshiro, Li, Min, Hwang, Tzyh-Chang
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995156/
https://www.ncbi.nlm.nih.gov/pubmed/21078867
http://dx.doi.org/10.1085/jgp.201010518