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Defects in nuclear pore assembly lead to activation of an Aurora B–mediated abscission checkpoint

Correct assembly of nuclear pore complexes (NPCs), which directly and indirectly control nuclear environment and architecture, is vital to genomic regulation. We previously found that nucleoporin 153 (Nup153) is required for timely progression through late mitosis. In this study, we report that disr...

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Detalles Bibliográficos
Autores principales: Mackay, Douglas R., Makise, Masaki, Ullman, Katharine S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995170/
https://www.ncbi.nlm.nih.gov/pubmed/21098116
http://dx.doi.org/10.1083/jcb.201007124