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Defects in nuclear pore assembly lead to activation of an Aurora B–mediated abscission checkpoint
Correct assembly of nuclear pore complexes (NPCs), which directly and indirectly control nuclear environment and architecture, is vital to genomic regulation. We previously found that nucleoporin 153 (Nup153) is required for timely progression through late mitosis. In this study, we report that disr...
Autores principales: | Mackay, Douglas R., Makise, Masaki, Ullman, Katharine S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995170/ https://www.ncbi.nlm.nih.gov/pubmed/21098116 http://dx.doi.org/10.1083/jcb.201007124 |
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