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ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma–lamin A complexes

As orchestrators of essential cellular processes like proliferation, ERK1/2 mitogen-activated protein kinase signals impact on cell cycle regulation. A-type lamins are major constituents of the nuclear matrix that also control the cell cycle machinery by largely unknown mechanisms. In this paper, we...

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Detalles Bibliográficos
Autores principales: Rodríguez, Javier, Calvo, Fernando, José, González, M., Casar, Berta, Andrés, Vicente, Crespo, Piero
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995174/
https://www.ncbi.nlm.nih.gov/pubmed/21115804
http://dx.doi.org/10.1083/jcb.201004067