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Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development

CS (chondroitin sulfate) is a glycosaminoglycan species that is widely distributed in the extracellular matrix. To understand the physiological roles of enzymes involved in CS synthesis, we produced CSGalNAcT1 (CS N-acetylgalactosaminyltransferase 1)-null mice. CS production was reduced by approxima...

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Detalles Bibliográficos
Autores principales: Watanabe, Yumi, Takeuchi, Kosei, Higa Onaga, Susumu, Sato, Michiko, Tsujita, Mika, Abe, Manabu, Natsume, Rie, Li, Minqi, Furuichi, Tatsuya, Saeki, Mika, Izumikawa, Tomomi, Hasegawa, Ayumi, Yokoyama, Minesuke, Ikegawa, Shiro, Sakimura, Kenji, Amizuka, Norio, Kitagawa, Hiroshi, Igarashi, Michihiro
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995422/
https://www.ncbi.nlm.nih.gov/pubmed/20812917
http://dx.doi.org/10.1042/BJ20100847