Structural determinants of PINK1 topology and dual subcellular distribution

BACKGROUND: PINK1 is a mitochondria-targeted kinase that constitutively localizes to both the mitochondria and the cytosol. The mechanism of how PINK1 achieves cytosolic localization following mitochondrial processing remains unknown. Understanding PINK1 subcellular localization will give us insight...

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Detalles Bibliográficos
Autores principales: Lin, William, Kang, Un Jung
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995477/
https://www.ncbi.nlm.nih.gov/pubmed/21092208
http://dx.doi.org/10.1186/1471-2121-11-90

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995477/
https://www.ncbi.nlm.nih.gov/pubmed/21092208
http://dx.doi.org/10.1186/1471-2121-11-90

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