Expression and Regulation of Cyclic Nucleotide Phosphodiesterases in Human and Rat Pancreatic Islets

As shown by transgenic mouse models and by using phosphodiesterase 3 (PDE3) inhibitors, PDE3B has an important role in the regulation of insulin secretion in pancreatic β-cells. However, very little is known about the regulation of the enzyme. Here, we show that PDE3B is activated in response to hig...

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Detalles Bibliográficos
Autores principales: Heimann, Emilia, Jones, Helena A., Resjö, Svante, Manganiello, Vincent C., Stenson, Lena, Degerman, Eva
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995729/
https://www.ncbi.nlm.nih.gov/pubmed/21152070
http://dx.doi.org/10.1371/journal.pone.0014191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995729/
https://www.ncbi.nlm.nih.gov/pubmed/21152070
http://dx.doi.org/10.1371/journal.pone.0014191

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