Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling

While Wnt-Frizzled (Fzd) signaling is critical in the pathophysiology of carcinomas, its role in human breast cancer has been difficult to establish. We show here that the adaptor protein Na(+)/H(+) Exchange Regulatory Factor1 (NHERF1), a protein abundantly expressed in normal mammary epithelium, re...

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Detalles Bibliográficos
Autores principales: Wheeler, David S., Barrick, Stacey R., Grubisha, Melanie J., Brufsky, Adam M., Friedman, Peter A., Romero, Guillermo
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995822/
https://www.ncbi.nlm.nih.gov/pubmed/20802536
http://dx.doi.org/10.1038/onc.2010.389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995822/
https://www.ncbi.nlm.nih.gov/pubmed/20802536
http://dx.doi.org/10.1038/onc.2010.389

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