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Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling

While Wnt-Frizzled (Fzd) signaling is critical in the pathophysiology of carcinomas, its role in human breast cancer has been difficult to establish. We show here that the adaptor protein Na(+)/H(+) Exchange Regulatory Factor1 (NHERF1), a protein abundantly expressed in normal mammary epithelium, re...

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Detalles Bibliográficos
Autores principales:	Wheeler, David S., Barrick, Stacey R., Grubisha, Melanie J., Brufsky, Adam M., Friedman, Peter A., Romero, Guillermo
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995822/ https://www.ncbi.nlm.nih.gov/pubmed/20802536 http://dx.doi.org/10.1038/onc.2010.389

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