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Multiple Linked Quantitative Trait Loci within the Tmevd2/Eae3 Interval Control the Severity of Experimental Allergic Encephalomyelitis in DBA/2J Mice

Theiler’s murine encephalomyelitis virus-induced demyelination (TMEVD) and experimental allergic encephalomyelitis (EAE) are the principal animal models of multiple sclerosis (MS). Previously we provided evidence that Tmevd2 and Eae3 may represent either a shared susceptibility locus or members of a...

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Detalles Bibliográficos
Autores principales: Spach, Karen M., Case, Laure K., Noubade, Rajkumar, Petersen, Chase B., McElvany, Ben, Zalik, Nathan, Hickey, William F., Blankenhorn, Elizabeth P., Teuscher, Cory
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995842/
https://www.ncbi.nlm.nih.gov/pubmed/20861860
http://dx.doi.org/10.1038/gene.2010.40