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Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor

Inactivation of von Hippel-Lindau tumor suppressor protein (pVHL) is associated with von Hippel-Lindau disease, an inherited cancer syndrome, as well as the majority of patients with sporadic clear cell renal carcinoma (RCC). While the involvement of pVHL in oxygen sensing through targeting HIFα sub...

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Detalles Bibliográficos
Autores principales: Liu, Weijun, Xin, Hong, Eckert, David T., Brown, Julie A., Gnarra, James R.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995849/
https://www.ncbi.nlm.nih.gov/pubmed/20802534
http://dx.doi.org/10.1038/onc.2010.395