Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB

Although cyclophilin A (CypA) has been reported to be over-expressed in cancer cells and solid tumors, its expression and role in glioblastomas have not been studied. Herein, we show that expression of CypA in human glioblastoma cell lines and tissues is significantly higher than in normal human ast...

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Detalles Bibliográficos
Autores principales: Sun, Shan, Wang, Qiuwei, Giang, An, Cheng, Cong, Soo, Chia, Wang, Cun-Yu, Liau, Linda M., Chiu, Robert
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Laboratory Investigation - Human/Animal Tissue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995866/
https://www.ncbi.nlm.nih.gov/pubmed/20454998
http://dx.doi.org/10.1007/s11060-010-0220-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995866/
https://www.ncbi.nlm.nih.gov/pubmed/20454998
http://dx.doi.org/10.1007/s11060-010-0220-y

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