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Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB
Although cyclophilin A (CypA) has been reported to be over-expressed in cancer cells and solid tumors, its expression and role in glioblastomas have not been studied. Herein, we show that expression of CypA in human glioblastoma cell lines and tissues is significantly higher than in normal human ast...
Autores principales: | Sun, Shan, Wang, Qiuwei, Giang, An, Cheng, Cong, Soo, Chia, Wang, Cun-Yu, Liau, Linda M., Chiu, Robert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995866/ https://www.ncbi.nlm.nih.gov/pubmed/20454998 http://dx.doi.org/10.1007/s11060-010-0220-y |
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