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An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice

AIMS/HYPOTHESIS: Loss of circadian clocks from all tissues causes defective glucose homeostasis as well as loss of feeding and activity rhythms. Little is known about peripheral tissue clocks, so we tested the hypothesis that an intrinsic circadian clock of the pancreas is important for glucose home...

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Detalles Bibliográficos
Autores principales: Sadacca, L. A., Lamia, K. A., deLemos, A. S., Blum, B., Weitz, C. J.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995870/
https://www.ncbi.nlm.nih.gov/pubmed/20890745
http://dx.doi.org/10.1007/s00125-010-1920-8